Category Archives: Longevity

The Tragic Misconstruction of the Human Life Cycle

Modern humans have somehow come to believe that the human life cycle stops in young adulthood. Choosing to forego the critical step of procreation — and spending almost all their resources trying to maintain themselves at the young adult stage … Continue reading

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Falling Through the Earth’s Centre: How Long to Reach the Other Side?

The gravitational effects on a body falling through the centre of the Earth to the other side, is an interesting problem. The video above introduces an idea or two which may be new to you, even if you have thought … Continue reading

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Happiness Deconstructed

What is Happiness? First, a few things that happiness IS NOT: bitter hostility, helpless loneliness, a despairing dearth of choices, a lack of personal confidence based upon genuine personal incompetence, the absence of any meaningful purpose. The Happiness of Pleasure … Continue reading

Posted in Biomedicine, Dangerous Child, Longevity, Philosophy | Tagged , , ,

Anti-Ageing Interventions

A Few Biomarkers or “Mileposts” of Ageing It will be very difficult to measure the success of anti-ageing interventions without using a number of validated biomarkers that reflect the current state of ageing of the organism or person. Here are … Continue reading

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Sweet AGE-ing: Focus on Advanced Glycation End-Products

Advanced glycation end products, (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars.[1] They can be a factor in aging and in the development or worsening of many degenerative diseases, such as diabetes, atherosclerosis, … Continue reading

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Newer Life Extension Pathways

Mitochondrial Health Microarray screening revealed that epigenetic downregulation of the nuclear-coded GCAT gene, which is involved in glycine production in mitochondria, is partly responsible for these aging phenotypes. Treatment of elderly fibroblasts with glycine effectively prevented the expression of these … Continue reading

Posted in Disruptive Technologies, Longevity, Practical Medicine | 1 Comment

Genes Out of Thin Air, and Other Wonders

Human DNA comprises 98% non-coding DNA and only 2% coding DNA. But that is not the end of the story. Noncoding DNA is defined as all of the DNA sequences within a genome that are not found within protein-coding exons, … Continue reading

Posted in Genetics and Gene Expression, Longevity, Science | Tagged | 6 Comments

At What Age Should a Woman Become Pregnant?

What are the Best Ages for Women to Become Pregnant Historically, across cultures, it has been the norm for older males to marry younger females, so that women bore children early in life. In recent years, with the widespread postponing … Continue reading

Posted in Fertility, Genetics and Gene Expression, Longevity, Medicine, Sex | Tagged , | 2 Comments

Young Men Pay for College While Boosting Female Sexuality and Healthy Pregnancies

London, UK — The secret to a long life may lie in the human sperm now. In a new study conducted by Graz University scientists in Austria, it has been found that a compound called spermidine, which is found is … Continue reading

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Fountain of Youth: Pouring Young Blood Into Old Bodies?

The search for the fountain of youth is following many different paths, including the “seven-fold path” of SENS, suspended animation via cryonic vitrification, tweaking the immune system to boost human resilience, increasing the length of telomeres, regenerative medicine, stem cells, … Continue reading

Posted in Longevity, Optimism, Regenerative Medicine | Tagged | 2 Comments